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Nitroglcerin for anal fissure

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Purpose: Topical nitrates have been shown to cause nitric oxide-mediated relaxation of the internal anal sphincter. Previous reports have suggested initial efficacy in the treatment of anal fissures. The aim of this study was to assess the longer-term usefulness of this treatment. Methods: Thirty-three patients with an anal fissure were treated with topical 0.

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Nitroglycerin ointment for anal fissures: effective treatment or just a headache?

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Local nitroglycerin for treatment of anal fissures: an alternative to lateral sphincterotomy?

Back to Anal fissure. Like other small cuts or tears to the skin, an anal fissure will often heal by itself within a few weeks. However, you should see a GP if you have an anal fissure as they can give you advice and medicines to help ease your symptoms and allow the fissure to heal more quickly. Most anal fissures will heal with treatment, although they can happen again easily, particularly if you do not follow self-help advice.

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Anal fissure

Most medical treatments of chronic anal fissure aim to reduce anal sphincter tone Cross et al. Glyceryl trinitrate, also known as nitroglycerin, is a vasodilator and muscle relaxant. When applied locally to the anus, it relaxes the anal sphincter. Anal fissure is a common and painful problem that involves a tear or ulcer in the squamous epithelium of the anus. It usually occurs between the ages of 20 and 40 with an equal distribution between men and women and a lifetime incidence of

The anus is the opening in the bottom where stool passes out of the body. When the skin in the anus develops a tear or a crack, it is called an anal fissure. Anal fissures may cause both bleeding and pain. The bleeding may be bright red and appear in the toilet or on toilet paper after wiping.